Friday, November 30, 2012

10 Minutes To Small Business Website Marketing | You Love Random

Post picture for 10 Minutes To Small Business Website Marketing

Small business website offered is an positively essential partial of your business?but if we take usually 10 mins and use a tips in this essay to set adult your offered correctly, your offered will many run itself. Website offered is never a same for any business as we competence have a bricks and trebuchet business to market, or maybe an Internet usually website business. These are dual unequivocally opposite businesses and we will have to collect out a best offered ideas to fit your business.

Think Before You Act

The series one problem we see with tiny businesses on a Internet is that their founders started a business yet any transparent offered goals. This is unequivocally easy to do?business founders unequivocally mostly tumble in adore with their product. They know a product is good, so they assume people will come to their website to get it.

But people won?t demeanour for something they don?t know exists. Marketing has to be partial of your sum business plan, so greatfully take a impulse and consider about how we can use a following techniques to confederate offered into your website.

Buying Advertisements

This does not meant plastering promotion on your website, it means promotion on other websites to marketplace yours.

The easiest approach to publicize your website is by shopping advertisements?but for many businesses this is a unequivocally cost-ineffective approach to attract website visitors.

Advertisement efficacy can be distributed regulating a unequivocally elementary formula. First demeanour during your accounting annals to figure out your website?s net income. Then use your website statistics module to figure out how many people have visited your website. Divide a net income by a series of visitors. For example: $1,000 net income divided by 10,000 visitors = $0.10 net income per visitor.

Following a instance above, if we compensate some-more than a dime per click in a Pay-Per-Click (PPC) announcement program, you?re going to remove money.

Using Ads to Test Small Business Website Marketing

But if advertisements are not cost effective tiny business website offered collection on their own, they can assistance we fast and low exam several offered strategies on your website.

First, we need a goal?an movement we wish your website business to take. This can be shopping a product, signing adult for a mailing list, withdrawal a comment, or anything else that we can use to make money.

Second, we need a approach to lane over brief durations of time how many people see your offered and how many people take your idea action. Most websites we work with use Google Analytics Goals for this.

Third, we need a offered we wish to test. We?ll plead offered ideas in a subsequent section.

Finally, we need to emanate advertisements that approach visitors to your marketing. When a visitors review a marketing, they?ll possibly perform a idea movement or they?ll go to some other site.

If a vast commission of your visitors perform a idea movement after reading a sold square of marketing, afterwards we know that offered technique is successful for your business and we can start regulating it to foster your business. On a flip side, if a offered doesn?t work, we can dump it immediately yet wasting some-more resources on it.

6 Specific Small Business Website Marketing Ideas

1. Guest posts: a lot of tiny businesses write guest blog posts to boost their page rank, yet a guest post can also expostulate trade to your site. To exam either guest posts are effective during attracting traffic, emanate an announcement to a guest post and lane how many clicks a announcement gets contra how many people click by a guest post to your site.

2. Quality content: write a super-high peculiarity blog post or essay for your site and, during a bottom, ask people to rate a post. (You might wish to try several opposite post rating systems?in my experience, some of them get some-more clicks than others.) Use your website statistics module to lane either or not people who rate a post frequency are expected to revisit other articles on your site and either they?re expected to come behind a subsequent day or week. For fast testing, emanate an announcement that drives people to that high-quality essay on your site.

3. Local vs. Global: see that geographic regions make we a many money. Create a fist page?a page that sells a sold product or encourages people to pointer adult for a mailing list?and afterwards place an announcement that is shown to usually a sold geographic region. When we find that segment creates we a many money, approach a rest of your offered efforts during attracting trade from that region.

4. Keyword testing: before we select site keywords, see either we can modify a trade they attract by fixation an announcement regulating a keyword word that points to your fist page. Test several associated keywords and concentration your site on a keyword that gets a many sales or sign-ups on your fist page.

5. Premium testing: one of a best ways to get people to pointer adult for a giveaway newsletter or other subscription is by charity them a reward (free) news or ebook, yet it creates a large disproportion what pretension we select for your report?some news titles will get some-more sign-ups than others. Before we compensate someone hundreds of dollars to write your news (or before we spend dozens of hours essay it yourself), emanate 5 or 10 opposite fist pages any for a opposite report, even yet zero of a reports exist. Use advertisements to approach trade during those fist pages to see that news gets a many sign-ups. When someone signs adult for any of a reports, imitation a brief blunder summary explaining that you?re carrying a news rewritten and that you?ll email it to them as shortly as it?s finished?and then, when we have your news written, follow adult by promulgation them a news underneath a many successful title.

I do this kind of contrast all a time as it puts we on a spot. One time we combined for videos as a reward to a product that we was selling. we usually wanted to exam if a reward would make a product sell more. Well it did and we was rushing around perplexing to emanate for videos for a bonus. It was utterly humorous yet it worked! There is zero like putting your feet in it initial to get a pursuit done.

6. Customer stealing: demeanour during a advertisements on your competitors? websites and emanate advertisements with a same keywords that approach to your website. These are a ideal business for you?not usually do they review your form of website, yet they?re peaceful to click on advertisements (which many people on a Web frequency do). Work unequivocally tough to make these people repeated business by, for example, signing them adult to your mailing list.

Conclusion

None of a ideas in this essay take some-more than 10 mins to set up, yet they can all fast assistance we build good tiny business website marketing.

This essay creatively seemed on Lets Build Websites and has been republished with permission.

Find out how to associate your calm with Business 2 Community.

Source: http://youloverandom.com/10-minutes-to-small-business-website-marketing/

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Oklahoma Baseball Adds Remillard

Junior college transfer from Northeastern Oklahoma A&M becomes 14th member of '14 class.

Nov. 28, 2012

Josh Ake
INF | R/R | 5-11 | 185
Readington, N.J. (Howard College)

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Keach Ballard
UTL | L/R | 6-0 | 172
Durant, Okla. (Murray State College)

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Niko Buentello
INF | L/R | 6-3 | 210
Lewisville, Texas (Lewisville HS)

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Jake Elliott
RHP | R/R | | 6-7 | 200
Coppell, Texas (Coppell HS)

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Alec Hansen
RHP | R/R | 6-7 | 210
Loveland, Colo. (Loveland HS)

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Bryant Hodge
RHP | R/R | 5-9 | 185
Moore, Okla. (Christian Heritage Academy)

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Chris Kohler
LHP | L/L | 6-3 | 205
Alta Loma, Calif. (Los Osos HS)

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Trey Michalczewski
INF | S\R | 6-3 | 200
Jenks, Okla. (Jenks HS)

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Sheldon Neuse
INF/RHP | R/R | 6-0 | 185
Fort Worth, Texas (Fossil Ridge HS)

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Jacob Nottingham
C | R/R | 6-3 | 210
Redlands, Calif. (Redlands HS)

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Travis Remillard
RHP | R/R | 6-0 | 200
Norman, Oka. (Northeastern Okla. A&M)

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Octavio Rodriguez
LHP | L/L | 6-4 | 192
El Paso, Texas (Franklin HS)

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Caleb Simpson
RHP | R/R | 6-4 | 210
Norman, Okla. (Seminole State)

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Kyle Stephens
RHP | R/R | 6-4 | 200
Edmond, Okla. (Edmond HS)

NORMAN, Okla.?- University of Oklahoma head baseball coach Sunny Golloway announced the addition of junior college right-handed pitcher Travis Remillard (Norman, Okla./Norman HS/Northeastern Oklahoma A&M) to the program's 2014 signing class Tuesday.


Remillard becomes the 14th member of the '14 signing class for the Sooners. The Sooners announced the addition of 10 high school student-athletes and three other junior college transfers earlier this month.


View a brief bio on Remillard below.

?Photo Gallery
High school: 10 | Junior College: 4
By State: Oklahoma-6, Texas-4, California-2, Colorado-1, New Jersey-1?
By Position: Pitcher-8, Infield-3, Catcher-1, Utility-1, Two-way-1

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RHP | R/R | 6-0 | 200?
Norman, Okla. (Norman HS/Northeastern Oklahoma A&M)

? Letterwinner at Northeastern Oklahoma A&M under head coach Roger Ward.
? Letterwinner at Norman High School under head coach Doug Gillis.
? Son of Cindy and Tony Remillard.

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Source: http://onlyfans.cstv.com/schools/okla/sports/m-basebl/spec-rel/112812aac.html

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How do I record a streaming video?

In this excerpt from Answercast #74 I look at both the technical and legal ramifications of downloading or recording streaming video from internet locations.

So this answer actually gets a little bit complicated in two ways. One is technology and the other is legality, of all things.

Let's start with the technology.

With respect to YouTube specifically, go out and Google the phrase "YouTube downloader". There are many pieces of software available out there that will let you directly download a YouTube video. You don't have do any recording at all.

All you really need to do is download the video file from YouTube directly and you'll have what you're looking for: an offline copy of the video.

Record your screen

Now, for other sources? Many of them are using "true streaming" where there, literally, is no file to download. The only solution I'm aware of (and I've actually done this a couple of times) is to use a screen recording application.

I happen to use Camtasia, which is kind-of a higher end utility. There are a couple of other alternatives out there (one of which may even be free, but the name escapes me - perhaps someone will actually comment on this article and give a suggestion on that.)

The bottom line is that you end up using a "screen recording" utility. You have to make sure that it's also recording the audio output that plays with the video. (Camtasia happens to.)

What that allows you to do is exactly as you describe: record what's happening on your screen. Then you can save it to a video file in any number of different formats; whatever you would like it to be.

So those are two ways of doing it. If you can, find a direct downloader specifically for YouTube. Otherwise, you end up having to use screen recording software; screen capturing software, much like (if not exactly) Camtasia.

Legalities of downloading

Now. Let's talk about the legalities for a minute.

The problem is that what you're doing is you're making a copy of this video. Many times (in fact, I would claim, in most cases) even when there's a YouTube download available, it's not formally supported. It may be illegal, or at least against the Terms of Service of the site.

In other words, you're not supposed to do what you're trying to do in most cases.

It's unfortunate, it really is. In my case specifically, the reason I actually want this (for things like YouTube) is that there are videos out there that are available in High Definition. They look great! The problem is my internet connection is slow enough that I can't actually stream the High Definition version. I would want to download it first and then play it.

A YouTube downloader would let me get the High Definition version and then play it while offline, without relying on my internet connection.

Nonetheless, I do believe that's against YouTube's term of service. Technically, it could be considered illegal.

So be very careful when you're doing this. Pay attention to what the law says or, at least, what the Terms of Service is. Most of these sites will tell you. It's something worth looking into it.

Obviously, I personally believe that there are perfectly ethical reasons to do this; my scenario being one of them. But nonetheless, that doesn't necessarily mean that it's legal.

Now, I do have to end this by saying I am not a lawyer and this isn't legal advice. But I do, at least, want to make you aware of the potential legal ramifications of doing what it is you're asking to do.

Source: http://ask-leo.com/how_do_i_record_a_streaming_video.html

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14 Writing Tips from Anne Lamott | Psychology Today

Tomorrow night, I?ll interview writer Anne Lamott at Symphony Space?here in New York City. I?m a longtime fan of her work, so am looking forward to hearing her speak about her writing and her process.

It?s especially gratifying for me to do this interview, because years ago, when I was still in law school, Anne Lamott and I were both bridesmaids in my college roommate?s wedding. I was so intimidated by her, a Real Writer, that I don?t think I spoke two words to her the entire time. The intense discomfort I felt around writers was one clue that helped me realize that I wanted to be a writer, myself.

So, in honor of Anne Lamott, here?s a tips list summarizing, very briefly, some of the points she makes in her terrific book on writing, Bird by Bird: Some Instructions on Writing and Life.

  1. Write regularly, whether you feel like writing or not, and whether you think what you?re writing is any good or not.
  2. Give yourself short assignments. Keep it manageable so you don?t get overwhelmed.
  3. Write sh**ty first drafts. (I?m not being prissy about the word choice, just don?t want to get hung up in spam filters.) Don?t expect a piece of writing to flow perfectly out of your fingers on the first go. Of all the points she makes, many people seem to find this one the most helpful.
  4. Let the Polaroid develop; in other words, observe, watch, listen, stay in the moment, until you understand what you want to write about.
  5. Know your characters.
  6. Let the plot grow out of the characters.
  7. ?If you find that you start a number of stories or pieces that you don?t ever bother finishing?it may be that there is nothing at their center about which you care passionately. You need to put yourself at their center, you and what you believe to be true or right.?
  8. Figure out ways to jam the transmissions from Radio KFKD, the interior station feeding doubts and criticism into your brain. Especially about jealousy of other writers.
  9. Have pen and paper ready at all times. (She always carries an index card.)
  10. Call around. Ask for help.
  11. Start a writing group.
  12. Write in your own voice.
  13. Being published brings a quiet joy, but it doesn?t transform your life, and eventually you have to write again.
  14. ?Devotion and commitment will be their own reward.?

One line from Bird by Bird was helpful to me recently. I?ve been feeling a bit panicky about whether I?m going to be able to figure out the structure for my next book; I?m always anxious about a project until I get my structure nailed down. I took heart from her admonition: ?Try to calm down, get quiet, breathe, and listen.?

What strategies for writing have you found to be helpful? Or for getting yourself to sit down and work on any big project?

Also ...

  • Speaking of writing: one of my secret goals, as I've been working on my own happiness projects, has been to inject the phrase "happiness project" into the common parlance. Today, I noticed, the New York Times ran an article entitled "The Happiness Project" that had nothing to do with my work. Victory!

Source: http://www.psychologytoday.com/blog/the-happiness-project/201211/14-writing-tips-anne-lamott

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CSN: MLB writers need to chill with Hall of Fame

November 28, 2012, 12:16 pm

With the Hall of Fame candidates released today by the Baseball Writers Association of America, Canada, Japan, Various Hispanic Nations and All The Ships At Sea, the moralists are back in full flight and plumage.

Oh, hurray.

The debate that always seems to happen on this subject is thus resumed, with no resolution or even advancement in thought on either side expected. In other words, let the apoplectic shouting resume.

In fact, let me add to it by pointing out something to those voters who prefer to make their annual petulant stand on performance enhancing drug use and Hall of Fame ? something they may have forgotten in their annual blood pressure spike.

YOU DON?T WORK FOR BASEBALL! YOU ARE NOT GUARDIANS OF THE GAME! IT IS NEITHER YOUR JOB, YOUR RESPONSIBILITY OR EVEN YOUR RIGHT TO KEEP THE GAME PURE OF MISCREANTS WHEN IT SHOWS EVERY DAY THAT IT DOESN?T WANT TO BE!

And might I add:

YOU SILLY SELF-DELUDED BASTARDS!

I just needed to get that last one off my chest. Sorry.

All the other arguments about whether Barry Bonds, Roger Clemens, et. al., deserve inclusion have been exhausted, to no effect. People long ago stopped listening anyway, which is why shouting is the only way to even get any aerobic exercise on this topic any more.

So let us deal with the new round of explanations and rationalizations in the only way that seems to make even a ripple ? by shouting. And in no particular order:

THE HALL OF FAME IS NOT CHURCH. IT IS THE HISTORY OF BASEBALL, FOR GOOD AND ILL. IF IT ISN?T, THEN WHY ARE THE MEN WHO DEFENDED THE COLOR LINE IN THE HALL? WHY IS TY COBB IN THE HALL? WHY IS KENESAW MOUNTAIN LANDIS IN THE HALL? THEY ARE PART OF THE HISTORY, TOO. REMEMBER?

Next:

GIVEN THAT THE OWNERS HAD BEEN WARNED ABOUT THE DANGERS OF STEROIDS IN PARTICULAR BACK IN 1988 AND DID NOTHING ABOUT IT FOR MORE THAN A DECADE, WASN?T PED USE THE INDUSTRY STANDARD FOR MORE THAN A DECADE? YES, IT WAS. THEIR RULES, NOT YOURS.

And then:

WHEN DID JOURNALISTS START DEFENDING THE ERADICATION OF PEOPLE AND FACTS TO ACHIEVE A DESIRED END FOR THE BENEFIT OF PEOPLE THEY ALLEGEDLY OBJECTIVELY COVER? IF YOU CAN ANSWER THAT WITH A WORD OTHER THAN ?NEVER,? YOU SHOULD PROBABLY QUIT YOUR JOB.

[RELATED: Bonds, Sosa, Clemens on 2013 HOF ballot]

Not to mention:

HOW IS IT DEFENSIBLE NOT TO VOTE FOR JEFF BAGWELL BASED ON A SUSPICION, AS YET NEITHER PROVEN NOR EVEN EVIDENCED, THAT HE MIGHT HAVE DONE SOMETHING AT SOME POINT TO EXPLAIN HIS ACHIEVEMENTS? YOU?RE COMFORTABLE WITH THAT LEVEL OF INTELLECTUAL DISHONESTY?

And might I add:

SINCE WHEN IS CRAIG BIGGIO?S CASE FOR INCLUSION ENHANCED BY THE NOTION THAT HE HAS NEVER BEEN SUSPECTED OF PED USE? IF I SAID OFF THE TOP OF MY HEAD THAT I THINK HE USED BRAZILIAN WOMBAT EXTRACT FOR SIX WEEKS TO HELP HIM TRANSITION TO THE RIGORS OF SECOND BASE IN 1992, CAN I KEEP HIM OFF MY BALLOT? DOES THIS MAKE ANY SENSE TO YOU AT ALL?

By the way, I?m voting for Craig Biggio, so don?t try to misconstrue that last one.

WHEN WERE YOU HIRED TO DEFEND THE MYTHICAL PURITY OF THE GAME? WHO PAID YOU TO DO THIS? YOUR WHY DO YOU HAVE A STAKE IN DISTORTING HISTORY, OR DEFENDING NUMBERS? WHY IS REALITY NOT GOOD ENOUGH FOR YOU?

And might I add a corollary:

ISN?T IT BETTER FOR YOUR CASE TO VOTE IN PLAYERS YOU KNOW OR THINK USED PERFORMANCE ENHANCERS SO THAT BASEBALL CAN LIVE WITH THE SHAME THAT COMES FROM LOOKING THE OTHER WAY ON WHAT WERE ACTUALLY FELONIES? I MEAN, IF YOU HAVE A STAKE IN CLEANING UP THE GAME, WHICH YOU SHOULDN?T, ISN?T REMINDING THE INDUSTRY OF ITS OCCASIONAL SYSTEMATIC FAILURES PART OF THAT JOB?

And finally, because my voice is giving out:

VOTE FOR WHOMEVER THE HELL YOU WANT. LET A THOUSAND FLOWERS BLOOM, AS THAT GRAND OLD BALL FAN MAO ZEDONG ONCE SAID. JUST DON?T TELL US YOU DID IT BECAUSE THE GAME DESERVES TO BE REPRESENTED BY THE FINEST CALIBER PEOPLE. BASEBALL IS ALL CLASSES OF PEOPLE, MISCREANTS, NOBLEMEN AND ALL POINTS IN BETWEEN, AND THAT'S WHAT IT DESERVES. YOU CAN?T CHANGE THAT, AND CASTING A VOTE WITH THAT IN MIND DISTORTS WHAT YOU SEE AND WRITE ABOUT.

And if you think baseball should reward only clean players and punish PED users, please remember this:

MELKY CABRERA JUST GOT A RAISE FROM HIS 2012 CONTRACT. IF BASEBALL IS FINE WITH THAT, WHY DO YOU THINK YOUR STANDARD FOR THEIR HALL SUPERCEDES THEIR OBVIOUS POSITION ON THE MATTER?

Okay. I?m going to melt down some cough drops and shoot them directly into my larynx now. I did the best I could. Plus, I called a lot of people I know and like ?silly, self-deluded bastards? in print. That, to me, is a very good day?s work.

Ray Ratto is a columnist for CSNBayArea.com

US Presswire images
AP Images

Source: http://www.csnbayarea.com/11/28/12/The-Hall-of-Fame-is-not-church-/nbcsportsgiants.html?blockID=807187&feedID=2796

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Thursday, November 29, 2012

Your Ideal PC Gaming Hardware

Your Ideal PC Gaming HardwareHere at Kotaku, not everyone is a fully-fledged PC gamer. But some of us would like to be.

Like a certain Tina who has a certain birthday coming up this Friday. Who also has a certain older brother who spoils her. See where I'm going with this?

So he and I will be doing our research and digging into the best parts to put into my soon-to-be glorious PC machine. But maybe you guys have a few suggestions. And maybe some of you are, like me, looking to chip off a piece of this whole "master race" business.

Let's share and weigh in on the absolute best pieces of hardware that would create the most optimal beast to run the shiniest of games.Your Ideal PC Gaming Hardware

Source: http://kotaku.com/5963907/what-do-you-put-inside-the-most-impressive-pc-gaming-machine-technology-has-to-offer

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Cork Meet ? 3 Day International Business Networking Event 10-12th ...

We who are lucky enough to live in Cork or who are from Cork don?t need reminding of the benefits of living and working in Cork, however, now more than ever, we need to compete for new business and to grow and sustain current businesses (and jobs)in the Cork Region. ?We have Cork Airport, Airport Business Park, Port of Cork , Ringaskiddy , Curraheen Science Park, University College Cork, Cork Institute of Technology and plan for much more, all of which help to attract people to the area. ?CorkMeet in conjunction with other event (Cork Innovate etc) focus and foster new business and new business ideas and business networking on a practical yet high end scale. ?I will certainly be attending and in conjunction with both local authorities executive and members help in ?spreading the word.

CorkMeet 2013 is a 3-day international business networking event taking place in Cork, Ireland, from 10-12 April. For full details go to www.corkmeet.ie or call 353 (0) 21 4320467.

CorkMeet 2013 is a not for profit partnership between Cork County Council and Cork City Council (local government), Cork County and City Enterprise Boards and Cork Chamber of Commerce.

About the Event:

This must attend event is open to Irish and international small and medium sized businesses from all sectors looking to expand into new markets and find new partners.

The event is relevant to all business sectors. Cork is an international centre of excellence in Pharma, ICT, PharmaChem, Food, Education, Manufacturing, Maritime and Tourism. It is home to some of world?s leading industries with companies such as Apple (European HQ), PepsiCo, Pfizers, EMC etc? being part of the economic fabric of the region for many years. These companies are sustained by SMEs of world class standard. It is a great place rich in industry. Come and meet them.

Each business will be offered 16 pre-scheduled one-to-one meetings with companies of their choice in a networking format and pre-selected from the CORKMEET 2013 business catalogue available online.

600 companies are expected to avail of more than 9,600 individual meetings, thus initiating thousands of business partnerships between SME?s in Ireland and overseas.

These meetings will be complimented by a business conference, a Gourmet Food event, informal dinner and workshops to facilitate further networking and informal meetings with the closing address by a high profile international speaker.

To express your interest in attending CorkMeet 2013 please email ita@corkceb.ie

Statistics from a previous CorkMeet events:

99% of those surveyed said they follow up with the companies they met.

93% said they would attend the next CorkMeet event.

90% organised meetings outside of their meeting schedules.

CORKMEET 2013 is Ireland?s Business Gathering event. Come to Cork and Be Part of it!

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Ita Murphy
Training Coordinator/Business Adviser
Cork City Enterprise Board
Room 101, Ground Floor

City Hall Building

Anglesea Street

Cork

Tel. 021 4961828
Fax. 021 4961869
www.corkceb.ie

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?Investing in Your Future?

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Source: http://www.deirdreforde.ie/posts/council-business/cork-meet-3-day-international-business-networking-event-10-12th-april-2013/

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More omnivore dilemmas: Seasonal diet changes can cause reproductive stress in primates

ScienceDaily (Nov. 28, 2012) ? When seasonal changes affect food availability, omnivores like blue monkeys adapt by changing their diets, but such nutritional changes may impact female reproduction, according to research published November 28 in the open access journal PLOS ONE by Steffen Foerster from Barnard College, and colleagues from Columbia University and the Smithsonian Institution.

The authors found that levels of fecal glucocorticoids (fGC), a stress marker, increased when female monkeys shifted their diet towards lower quality fallback foods, whereas the levels decreased when the monkeys had access to preferred foods like insects, fruits and young leaves.

They also found that lactating females and those in the later stages of pregnancy showed greater increases in the stress marker than females who were not in these stages of reproduction. According to the authors, their results suggest that these seasonal changes in food availability may affect inter-birth intervals in these primates, and also affect the timing of infant independence from mothers.

Foerster adds, ""While it was interesting to find that even subtle changes in dietary composition may have strong effects on female reproductive decisions, it is equally noteworthy that social stress was almost entirely absent from blue monkey societies. Our study makes the point that integrating behavioral, ecological, and hormonal measures can reveal adaptive behavioral and reproductive strategies that would otherwise be difficult to discern."

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Story Source:

The above story is reprinted from materials provided by Public Library of Science.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Steffen Foerster, Marina Cords, Steven L. Monfort. Seasonal Energetic Stress in a Tropical Forest Primate: Proximate Causes and Evolutionary Implications. PLoS ONE, 2012; 7 (11): e50108 DOI: 10.1371/journal.pone.0050108

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/strange_science/~3/NFsqAA79Ps4/121128182947.htm

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Family's economic situation influences brain function in children

ScienceDaily (Nov. 28, 2012) ? Children of low socioeconomic status work harder to filter out irrelevant environmental information than those from a high-income background because of learned differences in what they pay attention to, according to new research published in the open access journal Frontiers in Human Neuroscience.

Numerous studies in the past few years have begun to reveal how poverty affects brain development and function. In 2008, Amedeo D'Angiulli of Carleton University in Ottawa, Canada and his colleagues used electroencephalography (EEG) to measure the brain wave patterns associated with an auditory selective attention task in children of high and low socioeconomic status (SES).

They found that the two groups of children exhibited differences in theta brain waves in the frontal lobe, which plays an important role in attention. This suggested that each group of children recruits different neural mechanisms for this particular type of task, and that the lower SES children allocate additional resources to attending to irrelevant information.

"Socioeconomic environment shapes the way our neurocognitive functions develop in childhood and influence the way we learn to process information when we are adults so that we can be well adapted in a certain specific type of social environment," says D'Angiulli.

For their latest study, D'Angiulli and his colleagues recruited 28 children aged 12-14 from two schools in neighborhoods of disparate socioeconomic status. One of them was attended predominantly by children from a high income background, and the other largely by children from a low income background.

The researchers performed the study at the schools during an ordinary school day. Working in a mobile lab -- a van equipped with all the apparatus needed -- they took saliva samples from the participants throughout the day, to measure changes in the levels of the stress hormone cortisol, and asked them to complete three questionnaires about their emotional and motivational state, at different times.

In the afternoon, the participants' brain waves were recorded while they performed a task in which they heard different sounds being played simultaneously into both ears, and were required to press a button as fast as possible when they heard one particular sound.

There were no significant differences between the two groups in the accuracy or reaction time during the task. The researchers did, however, observe differences in brain wave patterns between the two groups. Higher SES children exhibited far larger theta waves in response to sounds they attended to than to than those they should have ignored. In the lower SES children, however, this pattern was reversed -- the theta waves evoked by the unattended sounds were much larger than those for the attended sounds.

There were also significant differences between the two groups in the contributions of the left and right hemispheres -- lower SES children exhibited stronger theta waves in the right frontal lobe in response to attended sounds.

Overall, the lower SES children had higher cortisol levels than the higher SES children during the school day, but the differences before and after the attention task were small, suggesting that the stress response of both groups to the task was similar. And the questionnaires revealed that both groups experienced similar levels of boredom and motivation throughout the day and a similar increase of boredom before the attention task.

The findings suggest that lower SES children have to exert more cognitive control to avoid attending to irrelevant stimuli than higher SES children, and that doing so therefore requires more mental effort. This may be because they live in more threatening environments, in which it might be advantageous to pay attention to a broad range of environmental stimuli which are not unambiguous distractions, and may turn out to be important for survival.

"We are now studying how other domains that may be related to attention, such as decision-making, may differ in individuals with different socioeconomic background," says D'Angiulli.

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Story Source:

The above story is reprinted from materials provided by Frontiers, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Amedeo D'Angiulli, Joanne Weinberg, Tim F. Oberlander, Ruth E. Grunau, Clyde Hertzman, Stefania Maggi. Frontal EEG/ERP correlates of attentional processes, cortisol and motivational states in adolescents from lower and higher socioeconomic status. Frontiers in Human Neuroscience, 2012; 6 DOI: 10.3389/fnhum.2012.00306

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/living_well/~3/UVoxc5MzAww/121128103947.htm

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Chulatep Senivongse commented on Michael Wolleben's group WiMAX Oil and Gas

Hallo all,

I am new to the group. I am the MD at disquom funktechnik in Germany. We are an ISP over here as well as wireless system integrator. Oil and Gas is definitely a topic of interest for us as we are doing work in the Middle East, but at the moment haven't tapped into this area.

The majority of our work has been with other ISPs, healthcare institutions and wireless surveilance. Can anybody in the group give me advice as to Tender resources or any means of getting our services know to Oil & Gas companies?

Source: http://www.wimax360.com/xn/detail/610217%3AComment%3A200166?xg_source=activity

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Massive Marsupials Once Swung from Treetops Down Under

Some 15 million years ago, mobs of 150-pound (70-kilogram) marsupials roamed the treetops of Australia's rain forests, researchers say.

Nimbadon lavarackorum belonged to a family of large-bodied marsupials known as the diprotodontids that went extinct about 11,000 years ago. During the diprotodontids' reign in Australia, they ranged from sheep-size wombatlike creatures to the mega-herbivore Diprotodon, which stood at 13 feet (4 meters) tall and weighed up to 6,100 pounds (2,800 kg).

Nimbadons were on the small-end of this spectrum, and they lived during the Middle Miocene (about 16 million to 11.6 million years ago). These ancient marsupials are best known from 26 different specimens found at the bottom of a vertical cave in northwestern Queensland, where a group of them apparently plunged to their deaths. In a new study, researchers examined Nimbadon bones and compared them with other species to get a clearer picture of how these ancient animals might have lived.

The researchers said they found striking similarities between Nimbadon skeletons and those of current koalas, including strong forelimbs, large claws and highly mobile shoulder and elbow joints. These features, combined with the Nimbadon's short hind limbs, suggest that the animals had excellent climbing and grasping skills and also could have used their long, flexible arms to suspend themselves from branches and reach for food and supports.

Even though the diprotodontids were thought to have lived on the ground, all these characteristics point to a life in the trees, which would make Nimbadons the largest herbivorous mammals to have ever lived in the forest canopies of Australia ? an ecological niche that is now empty, the researchers say.

"The findings presented here indicate that we are only beginning to understand the range of morphological and niche diversity displayed by this ecologically important and widespread group of Australasian marsupials ? the diprotodontids," the researchers concluded.

The study, led by a team from the University of New South Wales in Sydney, was published online Nov. 21 the journal PLoS ONE.

Follow LiveScience on Twitter @livescience. We're also on Facebook?& Google+.

Copyright 2012 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://news.yahoo.com/massive-marsupials-once-swung-treetops-down-under-132022576.html

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Wednesday, November 28, 2012

Pitch ? The road ahead for Compact SUV market in India

With the advent of vehicles like Mahindra Quanto, Premier Rio and Renault Duster launched in the country, the Compact SUV market is making a name for itself with more and more consumers moving towards this segment. Claiming to give an experience of both the worlds; a compact premium hatchback and an entry level sedan, the makers of these SUVs are pitching the product to appeal to a younger, professional and lifestyle oriented users. Why is India late in bringing this segment on road? And what is the future? Pitch finds out.

Vivek Nayer, CMO, Automotive Division, Mahindra & Mahindra

Vivek Nayer, CMO, Automotive Division, Mahindra & Mahindra

According to Vivek Nayer, CMO, Automotive Division, Mahindra and Mahindra, the brand that launched Quanto two months back, says that Mahindra is trying to create a new segment as the market for compact SUV was non-existent in India. He explains that this segment will appeal to hatchback owners, entry level sedan owners and SUV owners as well. There are areas and scope for improvement in each of these segments. For example, he says hatchbacks are compact, have decent mileage and have easy manoeuvrability but do not have the presence, high ground clearance or the space of an SUV. ?We believe that the compact SUV is the best of both worlds, it allows the user to get the feel of both the worlds. It is compact from the outside, easy to manoeuvre in the city, and at the same time spacious from the inside,? adds Nayer.

Change to compact
Umang kumar, Co-Founder and CEO Gaadi.com affirms that the segment has gained popularity, but only over the past few years in India. ?People in India now indulge in more outdoor activities compared to the past. This is the result of growing disposable income. For an average Indian family, a compact SUV makes sense because for its optimal proportions, practicality, usability, fuel economy and cost of ownership,? he adds.

But why are home grown brands coming out with compact SUVs now? Auto makers like Tata Motors and Mahindra & Mahindra have been making entry-level SUVs in the past. According to Kumar these products lacked the comfort and feel of the modern family cars and, hence, became more popular with cab operators instead. ?The compact SUV segment, which since the launch of the Renault Duster and Mahindra Quanto, has given the buyer an option of well-packaged, practical utility vehicle with a character of its own. Next up will be the Ford EcoSport while, Tata Motors is also thinking of a compact Aria,? he says.

This has been pushed further with the growing popularity of Utility Vehicles in the country as data suggests. According to reports from SIAM (Society of Indian Automobile Manufacturers), sales of Utility Vehicles grew by 55.83 per cent during April-September 2012 and 60.54 per cent during April-October 2012 as compared to the same period last year. April-October 2011 recoded domestic sales of 1,92,591 vehicles in the Utility Vehicle segment, while in 2012 it is 3,09,180 units.

Market evolution
Has the market evolved? No says Nayer, he adds that Mahindra is evolving the market. With the introduction of the Compact SUV Quanto, Mahindra claims to appeal to a wider audience and hopes to draw volumes from all the three segments, which includes SUVs, hatchbacks and sedans.

He believes that if all three segments are put together the market size is of one lakh vehicles per month. He says that the premium hatchback market size is 40,000 a month, entry level sedans size is 20,000 a month and SUV is another 40,000 a month. ?We are talking about a 90,000 plus market size out of which Quanto will get a share, as we have a production size of 2,500.

But is it true that models based on proven and global platforms are the way forward to build mass volumes in the country? Nayer says that internationally the ratio between cars to SUV in many markets like Malaysia and Europe are 40:60, 40 per cent SUV and 60 per cent car. ?In India the ratio is half of that, which is around 20 per cent. We believe that in time, the kind of offering we are giving to the consumers and as lifestyle, aspiration and standards of living improve, people will buy more and more SUV kind of products, which appeal to their needs,? he adds, citing at the Quanto.

According to a survey by Gaadi.com, the share of voice for compact SUVs is 36 per cent compared to others which stands at 64 per cent. Indexed Data show that Mahindra Quanto in the period from 16th October to 15th November got a score of 16 out of 100 in terms of share of voice, followed by Tata Safari at 15, and Renault Duster at 11.

Is price the only factor?
The Quanto stars at Rs 5.99 lakh (ex-showroom) and goes to Rs 7.5 lakh (ex showroom), while Maruti Ertiga starts at Rs 7.3 lakh (ex-showroom) for diesel, and Nissan Duster starts above Rs 8.1 lakh (ex-showroom). Is pricing the only factor that is driving the sales? And does this segment hold enough market share to drive volume buys? Gaadi.com?s Kumar cites figures from his company?s report, which says that the sales figures of October 2012 show that SUVs comprised 8 per cent of the total cars sold during the month. He adds, ?The newest addition to the compact SUV segment the Quanto, the sales of which slowly seem to be gaining momentum. Sales of the car increased by over 40 per cent month on month (m-o-m) post its launch in September 2012. The number Renault Dusters sold also increased by 28 per cent m-o-m.?

If the sales are steady and there is enough hype in this segment, then why is India opening up so late for the compact SUV segment? Nayer says that there are two reasons, internationally the SUV to car ratio is 40:60, because the per capita income is higher and the lifestyle is different.?That kind of lifestyle aspiration has recently come to India. In our country SUVs are bought only for utility purpose but of late people have started buying SUV for lifestyle purposes,? Nayer adds.

Murad Ali Baig, Auto expert

Murad Ali Baig, Auto expert

Murad Ali Baig, Auto Expert, says that, SUV today is a bit of a misnomer as the buyers are not into serious off-roading. He adds, ?They just buy something that looks like an SUV, which gives them that macho feel.? With the rising tide of the compact SUV market, Baig explicates that what the market is seeing is not compact SUVs but low cost SUVs. ?Therefore, the new cars like Renault Duster and some of the other cars are low cost vehicles and they give you a sense of an SUV but they are actually have limited real SUV capabilities. They are not proper off-roaders they are two wheel drives,? he further adds.

Urban cowboy or rugged terrain?
But is the retail strategy of foreign brands enough to counter the home grown brands in terms of the compact SUV market? Kumar says that, product marketing is one thing but, experiencing the product first hand can make or break a deal. As buyers become more educated about quality, driving dynamics, features and safety, it?s a never-ending fight between indigenous car makers and foreign brands. ?The strategy adopted by Indian car makers is to provide a car with a whole lot more features while pricing it low. The multi-nationals on the other hand offer better build quality, safety features and the likes,? he adds. The figures in the past couple of months according to Gaadi.com seem to be moving in a positive direction. According to the site, customers have welcomed the new compact SUV segment. More players like Ford with EcoSport and Tata Motors with Compact Aria, are expected to jump in the fray. Also according to the site, in terms of share of voice, 30 out of the 100 people who searched for SUVs showed interest in a compact SUV.

What then could be the possible challenges both home grown brands and foreign brands could face in the market? Kumar says that, when a manufacturer has a compact SUV under its portfolio the biggest challenge for any manufacturer is keeping the manufacturing costs in check. ?In a competitive scenario like India, pricing is crucial. Most local brands are able to offer their cars at a low price thanks to the localisation that goes into making them. A well spread dealer network also plays an important role when it comes to market penetration. Secondly, maintaining a set quality standard is as crucial as the pricing. The buyers have become more aware of safety features and overall build quality,? he adds.

With more than 15,25,488 passenger vehicles sold in April-October 2012 (SIAM), which also includes utility vehicles, compact or not, consumers are still having a tough time manoeuvring during peak hours. Will the Compact SUVs only bring a sense of ?presence? or ?machoism? on the streets or will they really help to cut through the tough traffic with space and ease? Only time will tell.

Source: http://pitchonnet.com/blog/2012/11/28/the-road-ahead-for-compact-suv-market-in-india/

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Mortgage Delinquencies and Foreclosures Decline in U.S.; St Louis ...

By Dennis Norman, on November 27th, 2012

dennis-norman-mortgage-delinquences-foreclosureIn October 7.03 percent of homeowners with a mortgage were delinquent on their loan payments, this is a decline of almost 5 percent from the month before and 7.19 percent less than the year before, according to Lenders Processing Services? First Watch report.? Foreclosure pre-sales (borrowers somewhere in the foreclosure process but have not yet lost their homes) declined 6.77 percent from the month before and was down 15.99 percent from a year ago.? LPS does not break out data specific to St. Louis but recent data from RealtyTrac showed that St Louis foreclosure activity increased over 10 percent in October from the month before and was up over 7 percent from a year ago, so St Louis may be lagging behind the national trend in terms of improvement in foreclosure rates.

Total U.S. loan delinquency rate (loans 30 or more days past due, but not in foreclosure): 7.03%
Month-over-month change in delinquency rate: -4.91%
Year-over-year change in delinquency rate: -7.19%
Total U.S. foreclosure pre-sale inventory rate: 3.61%
Month-over-month change in foreclosure presale inventory rate: -6.77%
Year-over-year change in foreclosure presale inventory rate: -15.99%
Number of properties that are 30 or more days past due, but not in foreclosure: (A) 3,500,000
Number of properties that are 90 or more days delinquent, but not in foreclosure: 1,543,000
Number of properties in foreclosure pre-sale inventory: (B) 1,800,000
Number of properties that are 30 or more days delinquent or in foreclosure: (A+B) 5,300,000
States with highest percentage of non-current* loans: FL, MS, NJ, NV, NY
States with the lowest percentage of non-current* loans: MT, WY, SD, AK, ND

Source: Lenders Processing Services

Related posts:

  1. Mortgage delinquencies decline in October; ? Foreclosures on the rise
  2. Mortgage delinquencies increase in November; ? Foreclosures decline from month before
  3. Mortgage delinquencies decline in August; down almost 12 percent from year ago
  4. Mortgage delinquencies continue to decline; good news for the real estate market!
  5. Mortgage deqlinquencies decline in September; Foreclosures on the rise

Source: http://stlouisrealestatenews.com/st-louis-foreclosures/mortgage-delinquencies-and-foreclosures-decline-in-u-s-st-louis-may-be-lagging-behind/

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Yankees make their move....Meanwhile, looking for a baseball fix Wednesday? How about trivia and a movie '61*' at the Yogi Berra Museum

?

First things first.

It looks like the Yankees -- slowly but surely -- will bring back the members of its 2012 starting rotation. Which is not a bad thing. The Yankee starters were not their downfall. It was the lack of clutch hitting and putting the ball out of play.

The Bombers re-signed Hiroki Kuroda on a one-year deal for $15 million and are closing in on Andy Pettitte, one year, $11 million.

Mariano Rivera will also be back in the fold and, probably Ichiro too.

Down the road, GM Brian Cashman will most likely re-up underrated Russell Martin and postseason hero Raul Ibanez.

The bottom line?

When the 2013 season begins, the Bombers will have lost Rafael Soriano and the postseason challenged Nick Swisher.

Soriano will be replaced by Mariano and the Yanks can find a bat to replace Swisher. How about Cody Ross or making a trade for Shin-Soo Choo.

To be continued......

?

TRIVIA AND A MOVIE AT YOGI'S

Billy Crystal?s acclaimed 61* ? his film about the summer in which Yankee sluggers Mickey Mantle and Roger Maris staged a captivating assault on Babe Ruth?s celebrated home run record - will be the subject of a fun Trivia Nite at the Yogi Berra Museum & Learning Center, tonight, Wednesday,?at 7 p.m.

The contest, conducted by the entertainment trivia company Trivia AD, will be followed by a screening of the film, which originally aired on HBO in 2001.

Questions will range from easy to, well, not so easy. For example: Which stadium was used to re-create old Yankee Stadium (A: Tiger Stadium). OK, so which stadium was used to re-create old Memorial Stadium in Baltimore? (A: Los Angeles Coliseum).

Individuals and teams are invited to register. Fee is $10 per person, with prizes given to the winners.

Next up on the Museum?s baseball movie trivia series is Field of Dreams on Dec. 12.

To RSVP or for more info: (973) 655-6891.

The Yogi Berra Museum & Learning Center is a nonprofit sports education center located on the campus of Montclair State University. Its mission is to preserve and promote the values of respect, sportsmanship, social justice and excellence through inclusive, culturally diverse, sports-based educational programs and exhibits.

Source: http://blog.silive.com/yankeeswatch/2012/11/yankees_make_their_movemeanwhi.html

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Ben Affleck As Entertainer Of The Year: Actor Covers Entertainment Weekly's New Issue

Ben Affleck Entertainer Of The Year

Ben Affleck has been named the Entertainer of the Year.

EW.com:

And EW?s Entertainer of the Year is? Ben Affleck!

Having captivated moviegoers both in front of and behind the camera with Argo, Ben Affleck earned the number one spot on our annual list of the most talented and original performers who entertained us in 2

Read the whole story at EW.com

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Source: http://www.huffingtonpost.com/2012/11/28/ben-affleck-entertainer-of-the-year-entertainment-weekly_n_2204613.html

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ScienceDaily: Gene News

ScienceDaily: Gene Newshttp://www.sciencedaily.com/news/health_medicine/genes/ Genes and Genetics News. Read today's medical research in genetics including what can damage genes, what can protect them, and more.en-usTue, 27 Nov 2012 16:49:07 ESTTue, 27 Nov 2012 16:49:07 EST60ScienceDaily: Gene Newshttp://www.sciencedaily.com/images/logosmall.gifhttp://www.sciencedaily.com/news/health_medicine/genes/ For more science articles, visit ScienceDaily.Gene linked to respiratory distress in babieshttp://www.sciencedaily.com/releases/2012/11/121127130256.htm Some infants are more susceptible to potentially life-threatening breathing problems after birth, and rare, inherited DNA differences may explain why, according to new research.Tue, 27 Nov 2012 13:02:02 ESThttp://www.sciencedaily.com/releases/2012/11/121127130256.htmNew understanding of X chromosome inactivationhttp://www.sciencedaily.com/releases/2012/11/121127101534.htm Scientists have broadened our understanding of how cells regulate silencing of the X chromosome in a process known as X-inactivation.Tue, 27 Nov 2012 10:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121127101534.htmNew mechanism for cancer progression discoveredhttp://www.sciencedaily.com/releases/2012/11/121127094311.htm Researchers have discovered an alternative mechanism for activating rhe oncogene Ras that does not require mutation or hormonal stimulus.Tue, 27 Nov 2012 09:43:43 ESThttp://www.sciencedaily.com/releases/2012/11/121127094311.htmProtein injection points to muscular dystrophy treatmenthttp://www.sciencedaily.com/releases/2012/11/121127094248.htm Scientists have discovered that injecting a novel human protein into muscle affected by Duchenne muscular dystrophy significantly increases its size and strength, findings that could lead to a therapy akin to the use of insulin by diabetics.Tue, 27 Nov 2012 09:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121127094248.htmChemical 'switches' for neurodegenerative diseases discoveredhttp://www.sciencedaily.com/releases/2012/11/121127093951.htm Researchers have identified and ?switched off? a chemical chain that causes neurodegenerative diseases such as Huntington?s disease, amyotrophic lateral sclerosis and dementia. The findings could one day be of particular therapeutic benefit to Huntington?s disease patients.Tue, 27 Nov 2012 09:39:39 ESThttp://www.sciencedaily.com/releases/2012/11/121127093951.htmMetabolic protein launches sugar feast that nurtures brain tumorshttp://www.sciencedaily.com/releases/2012/11/121126164003.htm PKM2 slips into nucleus to promote cancer; potential biomarker and drug approach discovered.Mon, 26 Nov 2012 16:40:40 ESThttp://www.sciencedaily.com/releases/2012/11/121126164003.htmPossible new treatment for Ewing sarcomahttp://www.sciencedaily.com/releases/2012/11/121126142855.htm Discovery of a new drug with high potential to treat Ewing sarcoma, an often deadly cancer of children and young adults, and the previously unknown mechanism behind it, come hand-in-hand in a new study.Mon, 26 Nov 2012 14:28:28 ESThttp://www.sciencedaily.com/releases/2012/11/121126142855.htmSurvival gene may be key to controlling HIV and hepatitishttp://www.sciencedaily.com/releases/2012/11/121126131349.htm A newly discovered gene that is essential for embryo survival could also hold the key to treating and potentially controlling chronic infections such as HIV, hepatitis and tuberculosis. The gene, called Arih2, is fundamental to the function of the immune system -- making critical decisions about whether to switch on the immune response to an infection.Mon, 26 Nov 2012 13:13:13 ESThttp://www.sciencedaily.com/releases/2012/11/121126131349.htmMicrobial 'missing link' discovered after man impales hand on tree branchhttp://www.sciencedaily.com/releases/2012/11/121126110737.htm Two years ago, a 71-year-old Indiana man impaled his hand on a branch after cutting down a dead tree. The wound caused an infection that led scientists to discover a new bacterium and solve a mystery about how bacteria came to live inside insects.Mon, 26 Nov 2012 11:07:07 ESThttp://www.sciencedaily.com/releases/2012/11/121126110737.htmTransposable elements reveal a stem cell specific class of long noncoding RNAshttp://www.sciencedaily.com/releases/2012/11/121125192838.htm Over a decade after sequencing the human genome, it has now become clear that the genome is not mostly ?junk? as previously thought. In fact, the ENCODE project consortium of dozens of labs and petabytes of data have determined that these ?noncoding? regions house everything from disease trait loci to important regulatory signals, all the way through to new types of RNA-based genes.Sun, 25 Nov 2012 19:28:28 ESThttp://www.sciencedaily.com/releases/2012/11/121125192838.htmNew molecular culprit linked to breast cancer progressionhttp://www.sciencedaily.com/releases/2012/11/121124090511.htm Researchers have uncovered a protein ?partner? commonly used by breast cancer cells to unlock genes needed for spreading the disease around the body. A report on the discovery details how some tumors get the tools they need to metastasize.Sat, 24 Nov 2012 09:05:05 ESThttp://www.sciencedaily.com/releases/2012/11/121124090511.htmNew insights into virus proteome: Unknown proteins of the herpesvirus discoveredhttp://www.sciencedaily.com/releases/2012/11/121123092132.htm The genome encodes the complete information needed by an organism, including that required for protein production. Viruses, which are up to a thousand times smaller than human cells, have considerably smaller genomes. Using a type of herpesvirus as a model system scientists have shown that the genome of this virus contains much more information than previously assumed. The researchers identified several hundred novel proteins, many of which were surprisingly small.Fri, 23 Nov 2012 09:21:21 ESThttp://www.sciencedaily.com/releases/2012/11/121123092132.htmScientists describe elusive replication machinery of flu viruseshttp://www.sciencedaily.com/releases/2012/11/121122152928.htm Scientists have made a major advance in understanding how flu viruses replicate within infected cells. The researchers used cutting-edge molecular biology and electron-microscopy techniques to ?see? one of influenza?s essential protein complexes in unprecedented detail. The images generated in the study show flu virus proteins in the act of self-replication, highlighting the virus?s vulnerabilities that are sure to be of interest to drug developers.Thu, 22 Nov 2012 15:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121122152928.htmProtein folding: Look back on scientific advances made as result of 50-year old puzzlehttp://www.sciencedaily.com/releases/2012/11/121122152910.htm Fifty years after scientists first posed a question about protein folding, the search for answers has led to the creation of a full-fledged field of research that led to major advances in supercomputers, new materials and drug discovery, and shaped our understanding of the basic processes of life, including so-called "protein-folding diseases" such as Alzheimer's, Parkinson's and type II diabetes.Thu, 22 Nov 2012 15:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121122152910.htmStep forward in regenerating and repairing damaged nerve cellshttp://www.sciencedaily.com/releases/2012/11/121121145638.htm Researchers recently uncovered a nerve cell's internal clock, used during embryonic development. This breakthrough could lead to the development of new tools to repair and regenerate nerve cells following injuries to the central nervous system.Wed, 21 Nov 2012 14:56:56 ESThttp://www.sciencedaily.com/releases/2012/11/121121145638.htmArchitecture of rod sensory cilium disrupted by mutationhttp://www.sciencedaily.com/releases/2012/11/121121145621.htm Using a new technique called cryo-electron tomography, scientists have created a three-dimensional map that gives a better understanding of how the architecture of the rod sensory cilium (part of one type of photoreceptor in the eye) is changed by genetic mutation and how that affects its ability to transport proteins as part of the light-sensing process.Wed, 21 Nov 2012 14:56:56 ESThttp://www.sciencedaily.com/releases/2012/11/121121145621.htmAging: Scientists further unravel telomere biologyhttp://www.sciencedaily.com/releases/2012/11/121121130933.htm Researchers have resolved the structure of that allows a telomere-related protein, Cdc13, to form dimers in yeast. Mutations in this region of Cdc13 put the kibosh on the ability of telomerase and other proteins to maintain telomeres.Wed, 21 Nov 2012 13:09:09 ESThttp://www.sciencedaily.com/releases/2012/11/121121130933.htmDrug resistance biomarker could improve cancer treatmenthttp://www.sciencedaily.com/releases/2012/11/121121130811.htm Cancer therapies often have short-lived benefits due to the emergence of genetic mutations that cause drug resistance. A key gene that determines resistance to a range of cancer drugs has been reported in a new study. The study reveals a biomarker that can predict responses to cancer drugs and offers a strategy to treat drug-resistant tumors based on their genetic signature.Wed, 21 Nov 2012 13:08:08 ESThttp://www.sciencedaily.com/releases/2012/11/121121130811.htmGenome packaging: Key to breast cancer developementhttp://www.sciencedaily.com/releases/2012/11/121121130703.htm Two recent studies delve into the role of chromatin modifying enzymes and transcription factors in tumour cells. In one, it was found that the PARP1 enzyme activated by kinase CDK2 is necessary to induce the genes responsible for the proliferation of breast cancer cells in response to progesterone. In another, extensive work has been undertaken to identify those genes activated by the administration of progesterone in breast cancer, the sequences that can be recognized and how these genes are induced.Wed, 21 Nov 2012 13:07:07 ESThttp://www.sciencedaily.com/releases/2012/11/121121130703.htmShort DNA strands in genome may be key to understanding human cognition and diseaseshttp://www.sciencedaily.com/releases/2012/11/121121130643.htm Previously discarded, human-specific ?junk? DNA represents untapped resource in the study of diseases like Alzheimer?s and autism.Wed, 21 Nov 2012 13:06:06 ESThttp://www.sciencedaily.com/releases/2012/11/121121130643.htmBiomarking time: Methylome modifications offer new measure of our 'biological' agehttp://www.sciencedaily.com/releases/2012/11/121121130633.htm In a new study, researchers describe markers and a model that quantify how aging occurs at the level of genes and molecules, providing not just a more precise way to determine how old someone is, but also perhaps anticipate or treat ailments and diseases that come with the passage of time.Wed, 21 Nov 2012 13:06:06 ESThttp://www.sciencedaily.com/releases/2012/11/121121130633.htmKidney tumors have a mind of their ownhttp://www.sciencedaily.com/releases/2012/11/121121104552.htm New research has found there are several different ways that kidney tumors can achieve the same result -- namely, grow.Wed, 21 Nov 2012 10:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121121104552.htmMechanism to repair clumped proteins explainedhttp://www.sciencedaily.com/releases/2012/11/121121104416.htm Clumped proteins can be dissolved with the aid of cellular repair systems -- a process of critical importance for cell survival especially under conditions of stress. Researchers have now decrypted the fundamental mechanism for dissolving protein aggregates that involves specific molecular chaperones.Wed, 21 Nov 2012 10:44:44 ESThttp://www.sciencedaily.com/releases/2012/11/121121104416.htmNovel mechanism through which normal stromal cells become cancer-promoting stromal cells identifiedhttp://www.sciencedaily.com/releases/2012/11/121121104401.htm New understanding of molecular changes that convert harmless cells surrounding ovarian cancer cells into cells that promote tumor growth and metastasis provides potential new therapeutic targets for this deadly disease, according to new research.Wed, 21 Nov 2012 10:44:44 ESThttp://www.sciencedaily.com/releases/2012/11/121121104401.htmNew test for tuberculosis could improve treatment, prevent deaths in Southern Africahttp://www.sciencedaily.com/releases/2012/11/121120194932.htm A new rapid test for tuberculosis (TB) could substantially and cost-effectively reduce TB deaths and improve treatment in southern Africa -- a region where both HIV and tuberculosis are common.Tue, 20 Nov 2012 19:49:49 ESThttp://www.sciencedaily.com/releases/2012/11/121120194932.htmEvolution of human intellect: Human-specific regulation of neuronal geneshttp://www.sciencedaily.com/releases/2012/11/121120194926.htm A new study has identified hundreds of small regions of the genome that appear to be uniquely regulated in human neurons. These regulatory differences distinguish us from other primates, including monkeys and apes, and as neurons are at the core of our unique cognitive abilities, these features may ultimately hold the key to our intellectual prowess (and also to our potential vulnerability to a wide range of 'human-specific' diseases from autism to Alzheimer's).Tue, 20 Nov 2012 19:49:49 ESThttp://www.sciencedaily.com/releases/2012/11/121120194926.htmRibosome regulates viral protein synthesis, revealing potential therapeutic targethttp://www.sciencedaily.com/releases/2012/11/121120132906.htm Rather than target RNA viruses directly, aiming at the host cells they invade could hold promise, but any such strategy would have to be harmless to the host. Now, a surprising discovery made in ribosomes may point the way to fighting fatal viral infections such as rabies.Tue, 20 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121120132906.htmHow does antibiotic resistance spread? Scientists find answers in the nosehttp://www.sciencedaily.com/releases/2012/11/121120121835.htm Microbiologists studying bacterial colonization in mice have discovered how the very rapid and efficient spread of antibiotic resistance works in the respiratory pathogen, Streptococcus pneumoniae (also known as the pneumococcus). The team found that resistance stems from the transfer of DNA between bacterial strains in biofilms in the nasopharynx, the area just behind the nose.Tue, 20 Nov 2012 12:18:18 ESThttp://www.sciencedaily.com/releases/2012/11/121120121835.htmScientists identify inhibitor of myelin formation in central nervous systemhttp://www.sciencedaily.com/releases/2012/11/121120100155.htm Scientists have discovered another molecule that plays an important role in regulating myelin formation in the central nervous system. Myelin promotes the conduction of nerve cell impulses by forming a sheath around their projections, the so-called axons, at specific locations -- acting like the plastic insulation around a power cord.Tue, 20 Nov 2012 10:01:01 ESThttp://www.sciencedaily.com/releases/2012/11/121120100155.htm'Obese but happy gene' challenges the common perception of link between depression and obesityhttp://www.sciencedaily.com/releases/2012/11/121120084725.htm Researchers have discovered new genetic evidence about why some people are happier than others. The scientists have uncovered evidence that the gene FTO -- the major genetic contributor to obesity -- is associated with an eight per cent reduction in the risk of depression. In other words, it's not just an obesity gene but a "happy gene" as well.Tue, 20 Nov 2012 08:47:47 ESThttp://www.sciencedaily.com/releases/2012/11/121120084725.htmTelomere lengths predict life expectancy in the wild, research showshttp://www.sciencedaily.com/releases/2012/11/121119213144.htm Researchers have found that biological age and life expectancy can be predicted by measuring an individual's DNA. They studied the length of chromosome caps -- known as telomeres -- in a 320-strong wild population of Seychelles Warblers on a small isolated island.Mon, 19 Nov 2012 21:31:31 ESThttp://www.sciencedaily.com/releases/2012/11/121119213144.htmCancer: Some cells don't know when to stophttp://www.sciencedaily.com/releases/2012/11/121119171403.htm Certain mutated cells keep trying to replicate their DNA -- with disastrous results -- even after medications rob them of the raw materials to do so, according to new research.Mon, 19 Nov 2012 17:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121119171403.htmMultiple sclerosis ?immune exchange? between brain and blood is uncoveredhttp://www.sciencedaily.com/releases/2012/11/121119163301.htm DNA sequences obtained from a handful of patients with multiple sclerosis have revealed the existence of an ?immune exchange? that allows the disease-causing cells to move in and out of the brain.Mon, 19 Nov 2012 16:33:33 ESThttp://www.sciencedaily.com/releases/2012/11/121119163301.htmFruit fly studies guide investigators to molecular mechanism frequently misregulated in human cancershttp://www.sciencedaily.com/releases/2012/11/121119132056.htm Changes in how DNA interacts with histones ?- the proteins that package DNA ?- regulate many fundamental cell activities from stem cells maturing into a specific body cell type or blood cells becoming leukemic. These interactions are governed by a biochemical tug of war between repressors and activators, which chemically modify histones signaling them to clamp down tighter on DNA or move aside and allow a gene to be expressed.Mon, 19 Nov 2012 13:20:20 ESThttp://www.sciencedaily.com/releases/2012/11/121119132056.htm3-D light switch for the brain: Device may help treat Parkinson's, epilepsy; aid understanding of consciousnesshttp://www.sciencedaily.com/releases/2012/11/121119114249.htm A new tool for neuroscientists delivers a thousand pinpricks of light to individual neurons in the brain. The new 3-D "light switch", created by biologists and engineers, could one day be used as a neural prosthesis that could treat conditions such as Parkinson's and epilepsy by using gene therapy to turn individual brain cells on and off with light.Mon, 19 Nov 2012 11:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121119114249.htmNew factor of genetic susceptibility to Alzheimer's diseasehttp://www.sciencedaily.com/releases/2012/11/121119104944.htm A large-scale international study has just discovered a gene for susceptibility to a rare disease providing evidence of the heterogeneous aetiology of Alzheimer's disease.Mon, 19 Nov 2012 10:49:49 ESThttp://www.sciencedaily.com/releases/2012/11/121119104944.htmBlood cancer gene BCL6 identified as a key factor for differentiation of nerve cells of cerebral cortexhttp://www.sciencedaily.com/releases/2012/11/121119093848.htm The cerebral cortex is the most complex structure in our brain and the seat of consciousness, emotion, motor control and language. In order to fulfill these functions, it is composed of a diverse array of nerve cells, called cortical neurons, which are affected by many neurological and neuropsychiatric diseases. Researchers have opened new perspectives on brain development and stem cell neurobiology by discovering a gene called BCL6 as a key factor in the generation of cortical neurons during embryonic brain development.Mon, 19 Nov 2012 09:38:38 ESThttp://www.sciencedaily.com/releases/2012/11/121119093848.htmMinority report: Insight into subtle genomic differences among our own cellshttp://www.sciencedaily.com/releases/2012/11/121118141530.htm Scientists have demonstrated that induced pluripotent stem cells -- the embryonic-stem-cell look-alikes whose discovery a few years ago won this year's Nobel Prize in medicine -- are not as genetically unstable as was thought.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141530.htmSkin cells reveal DNA's genetic mosaichttp://www.sciencedaily.com/releases/2012/11/121118141524.htm The prevailing wisdom has been that every cell in the body contains identical DNA. However, a new study of stem cells derived from the skin has found that genetic variations are widespread in the body's tissues, a finding with profound implications for genetic screening.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141524.htmLikely basis of birth defect causing premature skull closure in infants identifiedhttp://www.sciencedaily.com/releases/2012/11/121118141432.htm Geneticists, pediatricians, surgeons and epidemiologists have identified two areas of the human genome associated with the most common form of non-syndromic craniosynostosis premature closure of the bony plates of the skull.Sun, 18 Nov 2012 14:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121118141432.htmDNA packaging discovery reveals principles by which CRC mutations may cause cancerhttp://www.sciencedaily.com/releases/2012/11/121117184658.htm A new discovery concerning a fundamental understanding about how DNA works will produce a "180-degree change in focus" for researchers who study how gene packaging regulates gene activity, including genes that cause cancer and other diseases.Sat, 17 Nov 2012 18:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121117184658.htmHepatitis C treatment's side effects can now be studied in the labhttp://www.sciencedaily.com/releases/2012/11/121116161059.htm Adverse side effects of certain hepatitis C medications can now be replicated in the lab, thanks to a research team. The new method aids understanding of recent failures of hepatitis C antiviral drugs in some patients, and could help to identify medications that eliminate adverse effects. The findings may aid the development of safer and more effective treatments for hepatitis C and other pathogens such as SARS and West Nile virus.Fri, 16 Nov 2012 16:10:10 ESThttp://www.sciencedaily.com/releases/2012/11/121116161059.htmReconsidering cancer's bad guyhttp://www.sciencedaily.com/releases/2012/11/121116124644.htm Researchers have found that a protein, known for causing cancer cells to spread around the body, is also one of the molecules that trigger repair processes in the brain.Fri, 16 Nov 2012 12:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121116124644.htmGene distinguishes early birds from night owls and helps predict time of deathhttp://www.sciencedaily.com/releases/2012/11/121116124551.htm New research shows that a gene is responsible for a person's tendency to be an early riser or night owl -- and helps determine the time of day a person is most likely to die.Fri, 16 Nov 2012 12:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121116124551.htmClues to cause of kids' brain tumorshttp://www.sciencedaily.com/releases/2012/11/121116091226.htm Insights from a genetic condition that causes brain cancer are helping scientists better understand the most common type of brain tumor in children.Fri, 16 Nov 2012 09:12:12 ESThttp://www.sciencedaily.com/releases/2012/11/121116091226.htmArthritis study reveals why gender bias is all in the geneshttp://www.sciencedaily.com/releases/2012/11/121115210541.htm Researchers have pieced together new genetic clues to the arthritis puzzle in a study that brings potential treatments closer to reality and could also provide insights into why more women than men succumb to the disabling condition.Thu, 15 Nov 2012 21:05:05 ESThttp://www.sciencedaily.com/releases/2012/11/121115210541.htmClass of RNA molecules protects germ cells from damagehttp://www.sciencedaily.com/releases/2012/11/121115172255.htm Passing one's genes on to the next generation is a mark of evolutionary success. So it makes sense that the body would work to ensure that the genes the next generation inherits are exact replicas of the originals. Biologists have now identified one way the body does exactly that.Thu, 15 Nov 2012 17:22:22 ESThttp://www.sciencedaily.com/releases/2012/11/121115172255.htmQuick test speeds search for Alzheimer's drugs: Compound restores motor function and longevity to fruit flieshttp://www.sciencedaily.com/releases/2012/11/121115152655.htm Researchers report that an efficient, high-volume technique for testing potential drug treatments for Alzheimer's disease uncovered an organic compound that restored motor function and longevity to fruit flies with the disease.Thu, 15 Nov 2012 15:26:26 ESThttp://www.sciencedaily.com/releases/2012/11/121115152655.htmProtein-making machinery can switch gears with a small structural change process; Implications for immunity and cancer therapyhttp://www.sciencedaily.com/releases/2012/11/121115133414.htm For the past several years, research has focused on the intricate actions of an ancient family of catalytic enzymes that play a key role in translation, the process of producing proteins. In a new study, scientists have shown that this enzyme can actually also work in another fundamental process in humans.Thu, 15 Nov 2012 13:34:34 ESThttp://www.sciencedaily.com/releases/2012/11/121115133414.htmPlant derivative, tanshinones, protects against sepsis, study suggestshttp://www.sciencedaily.com/releases/2012/11/121115133312.htm Researchers have discovered that tanshinones, which come from the plant Danshen and are highly valued in Chinese traditional medicine, protect against the life-threatening condition sepsis.Thu, 15 Nov 2012 13:33:33 ESThttp://www.sciencedaily.com/releases/2012/11/121115133312.htmStructure of enzyme topoisomerase II alpha unravelled providing basis for more accurate design of chemotherapeutic drugshttp://www.sciencedaily.com/releases/2012/11/121115132903.htm Medical researchers have for the first time described the structure of the active site core of topoisomerase II alpha, an important target for anti-cancer drugs. The type II topoisomerases are important enzymes that are involved in maintaining the structure of DNA and chromosome segregation during both replication and transcription of DNA. One of these enzymes, topoisomerase II alpha, is involved in the replication of DNA and cell proliferation, and is highly expressed in rapidly dividing cancer cells.Thu, 15 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121115132903.htmNewly discovered enzyme important in the spreading of cancerhttp://www.sciencedaily.com/releases/2012/11/121115132901.htm Enzyme hunters at UiO have discovered the function of an enzyme that is important in the spreading of cancer. Cancer researchers now hope to inhibit the enzyme.Thu, 15 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121115132901.htmGenetics point to serious pregnancy complication, pre-eclampsiahttp://www.sciencedaily.com/releases/2012/11/121115132613.htm New research has revealed a genetic link in pregnant moms - and their male partners - to pre-eclampsia, a life-threatening complication during pregnancy.Thu, 15 Nov 2012 13:26:26 ESThttp://www.sciencedaily.com/releases/2012/11/121115132613.htmMolecular mechanisms underlying stem cell reprogramming decodedhttp://www.sciencedaily.com/releases/2012/11/121115132344.htm Thanks to some careful detective work, scientist better understand just how iPS cells form ? and why the Yamanaka process is inefficient, an important step to work out for regenerative medicine. The findings uncover cellular impediments to iPS cell development that, if overcome, could dramatically improve the efficiency and speed of iPS cell generation.Thu, 15 Nov 2012 13:23:23 ESThttp://www.sciencedaily.com/releases/2012/11/121115132344.htmSurprising genetic link between kidney defects and neurodevelopmental disorders in kidshttp://www.sciencedaily.com/releases/2012/11/121115132342.htm About 10 percent of kids born with kidney defects have large alterations in their genomes known to be linked with neurodevelopmental delay and mental illness, a new study has shown.Thu, 15 Nov 2012 13:23:23 ESThttp://www.sciencedaily.com/releases/2012/11/121115132342.htmEven moderate drinking in pregnancy can affect a child's IQhttp://www.sciencedaily.com/releases/2012/11/121114172833.htm Relatively small levels of exposure to alcohol while in the womb can influence a child's IQ, according to a new study using data from over 4,000 mothers and their children.Wed, 14 Nov 2012 17:28:28 ESThttp://www.sciencedaily.com/releases/2012/11/121114172833.htmGene nearly triples risk of Alzheimer's, international research team findshttp://www.sciencedaily.com/releases/2012/11/121114171710.htm A gene so powerful it nearly triples the risk of Alzheimer's disease has been discovered by an international team of researchers. It is the most potent genetic risk factor for Alzheimer's identified in the past 20 years.Wed, 14 Nov 2012 17:17:17 ESThttp://www.sciencedaily.com/releases/2012/11/121114171710.htmDiscovery could lead to faster diagnosis for some chronic fatigue syndrome caseshttp://www.sciencedaily.com/releases/2012/11/121114171708.htm For the first time, researchers have landed on a potential diagnostic method to identify at least a subset of patients with chronic fatigue syndrome - testing for antibodies linked to latent Epstein-Barr virus reactivation.Wed, 14 Nov 2012 17:17:17 ESThttp://www.sciencedaily.com/releases/2012/11/121114171708.htmResearch breakthrough could halt melanoma metastasis, study suggestshttp://www.sciencedaily.com/releases/2012/11/121114153227.htm In laboratory experiments, scientists have eliminated metastasis, the spread of cancer from the original tumor to other parts of the body, in melanoma by inhibiting a protein known as melanoma differentiation associated gene-9 (mda-9)/syntenin.Wed, 14 Nov 2012 15:32:32 ESThttp://www.sciencedaily.com/releases/2012/11/121114153227.htmPig genomes provide massive amount of genomic data for human healthhttp://www.sciencedaily.com/releases/2012/11/121114134512.htm Researchers provide a whole-genome sequence and analysis of number of pig breeds, including a miniature pig that serves a model for human medical studies and therapeutic drug testing.Wed, 14 Nov 2012 13:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121114134512.htm

Source: http://www.sciencedaily.com/rss/health_medicine/genes.xml

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